| 摘要 |
<p>NEW MATERIAL:A compound of formula I (R<1> is pyrimidyl which may have 1-4C alkyl-substituent group; R<2> is carboxyl-protecting group). EXAMPLE:4-( 4, 6-Dimethylpyrimidin-2-yl )dithio-2-oxoazetidine-1-(2-isopropenyl)ace tic acid p-nitrobenzyl ester. USE:A synthetic intermediate for a compound having beta-lactamase inhibiting action. PREPARATION:The compound of formula I can be produced by reacting a penicilanic acid sulfoxide derivative of formula II with a mercapto derivative of formula R<1>SH in a solvent such as THF, benzene, etc., at 50-150 deg.C for 0.5-10hr.</p> |
