CATECHIN COATED ASCORBIC ACID AND METHOD

摘要

Coating of certain pharmaceuticals such as ascorbic acid with a heavy-metal-chelating substance, such as catechin, to prevent the development of mutagens like ''ascorbate-free-radical'' in the body, due to the action of cupric ions on ascorbic acid. In a preferred embodiment, ascorbic acid tablets or core particles are coated with d-catechin in order to produce dosage structures which shield the ascorbic acid from oxidation catalyzed by heavy metal ions. As the catechin coating is released in the stomach, it binds the heavy metal ions by chelation and prevents or minimizes the interaction of copper and ascorbic acid.