发明名称 SF-2370 SUBSTANCE DERIVATIVE AND PRODUCTION THEREOF
摘要 NEW MATERIAL:A compound expressed by formula I (X represents amino, alkylamino, dialkylamino, benzylamino, morpholino or pyrrolidino) and acid addition salt thereof. USE:A remedy for hypertension and a diuretic. PREPARATION:A compound expressed by formula II, a reactive derivative at the hydroxymethyl group thereof or an epoxy derivative expressed by formula III is reacted with ammonia, an amine expressed by the formula R-NH2 (R represents alkyl or benzyl) or an amine expressed by formula IV (R' represents alkyl or two R' groups may form morpholine or pyrrolidino together with the adjacent N atom of the imino group).
申请公布号 JPS62240689(A) 申请公布日期 1987.10.21
申请号 JP19860078249 申请日期 1986.04.07
申请人 MEIJI SEIKA KAISHA LTD 发明人 KOYAMA MASAO;HACHISU MITSUGI;OTANI NORIKO;SEZAKI MASAJI;KONDO SHINICHI
分类号 A61K31/55;A61P7/10;A61P9/12;C07D209/00;C07D273/00;C07D307/00;C07D498/22 主分类号 A61K31/55
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