摘要 |
NEW MATERIAL:A compound expressed by formula I (X represents amino, alkylamino, dialkylamino, benzylamino, morpholino or pyrrolidino) and acid addition salt thereof. USE:A remedy for hypertension and a diuretic. PREPARATION:A compound expressed by formula II, a reactive derivative at the hydroxymethyl group thereof or an epoxy derivative expressed by formula III is reacted with ammonia, an amine expressed by the formula R-NH2 (R represents alkyl or benzyl) or an amine expressed by formula IV (R' represents alkyl or two R' groups may form morpholine or pyrrolidino together with the adjacent N atom of the imino group). |