发明名称 N-acylpyrrolidine derivative and synthesis and use thereof
摘要 The present invention relates to N-acylpyrrolidine derivatives of the general formula (I): <IMAGE> (I) wherein R1 is a hydrogen atom, a C1-4 alkyl group or the phenyl group, with the proviso that when R1 is a hydrogen atom, R2 is phenoxy group, benzoyl, the phenyl group, or a phenyl group which is mono-substituted by a halogen atom or a C1-4 alkoxy group, and that when R1 is a C1-4 alkyl group or the phenyl group, R2 is an aralkyl group of 7 to 10 carbon atoms, a C1-4 alkyl group, the phenyl group or a phenyl group mono-substituted by a halogen atom or a C1-4 alkoxy group; or R1 and R2 together form an unsubstituted benzylidene group or a benzylidene group which may be mono-substituted by a C1-4 alkoxy group; wherein n is an integer of 0 to 5; and pharmaceutical compositions thereof which are useful as anti-amnesic agents.
申请公布号 US4701465(A) 申请公布日期 1987.10.20
申请号 US19860852711 申请日期 1986.04.16
申请人 SUNTORY LIMITED 发明人 TANAKA, TAKAHARU;SAITOH, MASAYUKI;HASHIMOTO, MASAKI;HIGUCHI, NAOKI
分类号 A61K31/40;A61K31/401;A61P25/28;A61P43/00;C07D207/08;C07D207/16;C12N9/99;(IPC1-7):A61K31/40 主分类号 A61K31/40
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