Acyl phosphate salts and their use

摘要

This invention consists of the production of a salt of acyl phosphate in an aqueous solution by a process which involves (1) acylation of phosphoric acid (H3PO4) with an acid anhydride of the general formula RCOX, where R can be hydrogen or a lower alkyl or aryl group having from 1 to 10 carbon atoms, and X can be a leaving group of the general formula OR, OCOR, X or NR2, followed by (2a) extraction of acyl phosphate to water by treatment of the reaction mixture with an aqueous bicarbonate or hydroxide solution or other basic aqueous solution, if the reaction is carried out in non-aqueous solvent or (2b) in the case where water has been used as reaction solvent acidification with acid or acid form of a carbon exchange resin. After (3) extraction of residual carboxylic acid from the resulting acidic aqueous mixture using a solvent in which the acid is soluble but with which water does not mix, the remaining aqueous solution of acyl phosphate is (4) neutralized by addition of a base such as sodium or potassium hydroxide.