| 摘要 |
NEW MATERIAL:The compound of formula I (R is lower alkoxycarbonyl, phenyl-lower alkenyl, etc.; R1 is H, halogen, OH, lower alkoxy, etc.; R2 is H, halogen, lower alkoxy, nitro, etc.; R3 is H, halogen, lower alkoxy, amino, etc.; R4 is H, halogen, lower alkoxy, nitro, etc.; R5 is H, halogen, lower alkoxy, etc.; X is lower alkylene.; etc.) and its acid addition salt. EXAMPLE:N-[(4-benzyl-2-morpholinyl)methyl]-6-bromo-2,3-dimethylbenzamide. USE:A drug. An antiemetic or a digestive tract function promoting agent. PREPARATION:A compound of formula I wherein R is R' and R1 is R1' can be produced by reacting a compound of formula II (R1' is same as R1 except for carboxyl-substituted lower alkoxy) with a compound of formula III (R' is same as R except for carboxyl-containing group). |
