Androstane series dehydro-steroid prepn.

摘要

A 9(11)-dehydro steroid, used in prepn. of cortico-steroids, is made by (a) dissolving a 9 alpha-hydroxy androstane in an organic base and reacting with benzene sulphonyl chloride; and (b) dissolving the androstane benzeno-sulphinate formed in chloroform, adding an organic acid and silica gel and heating under reflux.