| 发明名称 |
Modified enzyme. |
| 摘要 |
<p>A fibrinolytically active tissue-type plasminogen activator which has been modified: (a) in the region of the growth factor domain, and (b) to provide an amino acid without a positively charged side chain in place of lysine at position 277.</p> |
| 申请公布号 |
EP0241209(A1) |
申请公布日期 |
1987.10.14 |
| 申请号 |
EP19870302836 |
申请日期 |
1987.04.01 |
| 申请人 |
BEECHAM GROUP PLC |
发明人 |
BROWNE, MICHAEL JOSEPH;ROBINSON, JEFFREY HUGH |
| 分类号 |
A61K38/00;C12N9/72;(IPC1-7):C12N15/00;C12N9/64;A61K37/54 |
主分类号 |
A61K38/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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