Peptide derivatives and activity measuring method of physiologically active substances using the same as substrates.

摘要

Activities of physiologically active substances such as peptidases, proteases, transferases, phosphatases, protein kinase and the like enzymes can be measured specifically with high sensitivity by using as a substrate a peptide derivative having 2 to 15 amino acid units and a group which can emit fluorescence and/or absorb ultraviolet light as at least one terminal group. Their general formula: R @-A@-A-A @-R@ (I) or R @-A@-A@-R @ (II) idases