| 摘要 |
<p>MB 45021 IMPROVED PROCESS FOR REMOVING PYROGENS UTILIZING A HYDROPHOBIC MICROPOROUS MEMBRANE There is disclosed an improved process for removing pyrogens from a feed liquid selected from the group consisting of water and aqueous solutions containing said pyrogens, at a concentration of from about 0.1 to about 50 ng/ml, comprising the steps of contacting a feed side of a specified hydrophobic microporous membrane with said feed liquid, allowing said liquid to pass through said membrane, and recovering said liquid from a filtrate side of said membrane, said steps being terminated before said membrane becomes saturated with pyrogens. There is also disclosed an improved process for simultaneously removing pyrogens and particulate matter from a feed liquid selected from the group consisting of water and aqueous solutions containing said particulate matter and containing said pyrogens, at a concentration of from about 0.1 to about 50 ng/ml, comprising the steps of contacting a feed side of a specified hydrophobic microporous membrane with said feed liquid, allowing said liquid to pass through said membrane, and recovering said liquid from a filtrate side of said membrane, said steps being terminated before said membrane becomes saturated with pyrogens. The membrane used in the processes of the present invention is characterized by being made of polypropylene, being substantially skinless, and having (a) a bubble point of about 25 to about 50 psi; (b) a thickness of about 3 to about 7 mils; (c) a nitrogen flow rate of at least 0.5 liters per square centimeter-minute; (d) a burst strength of at least 10 psi; and (e) an S value of about 15, or less.</p> |
