| 摘要 |
<p>METHOD FOR PERCUTANEOUSLY ADMINISTERING PHYSIOLOGICALLY ACTIVE AGENTS USING AN ADJUVANT, A SOLVENT AND A DIOL MODERATOR A method of percutaneously administering a physiologically active agent which comprises applying to the skin of a mammal a physiologically active agent in a carrier system which comprises at least one adjuvant, at least one solvent and at least one diol moderator. The adjuvant can be selected from aliphatic hydrocarbons, halogen substituted aliphatic hydrocarbons, alcohol esters of aliphatic carboxylic acids, mono- or di-ethers, ketones, higher monoalcohols or mixtures thereof. The solvent can be selected from thioglycerols, lactic acid and esters thereof, cyclic ureas, compounds represented by the general formula R1R2NCONR3R4, pyrrolidone-type compounds, amides, lactones or mixtures thereof.</p> |
