| 发明名称 |
A PROCESS FOR THE PURIFICATION,SOLUBILIZATION AND/OR DETOXIFICATION OF PROTEIN ANTIGENS OF BACTERIA OF THE BORDETELLA GENUS USING A CARBONATE BUFFER AND AN ACELLULAR ANTI-WHOOPING COUGH VACCINE |
| 摘要 |
A method for the purification, solubilization and/or detoxification of protein antigens of bacteria of the Bordetella genus involves the use of a carbonate buffer having a pH of 8.3 to 11.6. An acellular anti-whooping cough vaccine containing active principles in this carbonate buffer is also disclosed. |
| 申请公布号 |
ZA8702712(B) |
申请公布日期 |
1987.10.05 |
| 申请号 |
ZA19870002712 |
申请日期 |
1987.04.15 |
| 申请人 |
MERIEUX INST |
发明人 |
MARIE-JOSE B. QUENTIN-MILLET;FRANCOIS ARMINJON |
| 分类号 |
C07K1/16;A61K39/00;A61K39/095;A61K39/10;C07K1/00;C07K1/107;C07K1/14;C07K1/22;C07K14/005;C07K14/195;C07K14/235;C07K14/41;C12P21/00;C12R1/01 |
主分类号 |
C07K1/16 |
| 代理机构 |
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代理人 |
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