发明名称 DIHYDROPYRIDINE SPRAY,PROCESS FOR ITS PREPARATION AND ITS PHARMACEUTICAL USE
摘要 A sprayable liquid formulation comprising, per 100 ml of the formulation, (a) 0.2 to 5 grams of a dihydropyridine of the formula <IMAGE> in which R1 and R2 each independently is alkyl with 1 to 10 carbon atoms optionally substituted by alkoxy with 1 to 3 carbon atoms, trifluoromethyl, halogen or N-methyl-N-benzylamino, R3 is alkyl with 1 to 4 carbon atoms, cyano or hydroxymethyl, and X is a nitro group, one or two chlorine groups or the ring member =N-O-N=, (b) 10 to 40 grams of polyethylene glycol with an average molecular weight of 200 to 600, (c) 25 to 60 grams of ethyl alcohol, and (d) 3 to 15 grams of polyvinylpyrrolidine with an average molecular weight of 12000 to 30000.
申请公布号 ZA8609448(B) 申请公布日期 1987.09.30
申请号 ZA19860009448 申请日期 1986.12.17
申请人 BAYER AKTIENGESELLSCHAFT 发明人 AHMED HEGASY;KLAUS-DIETER RAEMSCH
分类号 A61K31/455;A61K9/00;A61K9/12;A61K31/44;C07D211/90;C09K3/30 主分类号 A61K31/455
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