| 摘要 |
The invention provides a dosage form (10) for delivering the beneficial drugs (17) pseudoephedrine and brompheniramine to an environment of use, the dosage form comprising: a) a semi-permeable wall (12), permeable to the passage of fluid present in the environment of use but substantially impermeable to the passage of the drug, which wall surrounds and defines, b) a compartment 16 containing a dosage amount of a beneficial agent (17) for delivery to the environment of use at a controlled rate, and c) at least one passageway (14) in the wall (12) for connecting the interior of the compartment with the environment of use, characterized by a lamina (13) comprising a beneficial drug disposed upon the exterior of the semi-permeable wall (12), said lamina being adapted for transfer of a beneficial agent to the environment of use for immediate therapeutic effect. |
