Anti-diabetic pharmaceutical forms and the preparation thereof
摘要
The invention is directed to novel galenic preparation forms for providing an oral anti-diabetic agent having an improved release of active substance and processes for producing these preparation forms. The novel pharmaceutical compositions are characterized in that the onset of the activity and the duration of activity are adapted to the particular needs of diabetics with regard to proper control of the metabolism and the associated proper release of insulin. A basic or acidic excipient in a solvent is added to the anti-diabetic active substance in a quantity such that the active substance is made soluble, and then a solubilizing agent is added. Polyvinyl pyrrolidone is dissolved as carrier in this solution, but the carrier may simultaneously serve as the solubilizing adjuvant. This solution is further processed with other excipients to form corresponding preparation forms.
申请公布号
US4696815(A)
申请公布日期
1987.09.29
申请号
US19840615892
申请日期
1984.05.31
申请人
SCHEPKY, GOTTFRIED;BRICKL, ROLF;RUPPRECHT, ECKHARD;GREISCHEL, ANDREAS
发明人
SCHEPKY, GOTTFRIED;BRICKL, ROLF;RUPPRECHT, ECKHARD;GREISCHEL, ANDREAS