| 摘要 |
Compounds of Formula I <IMAGE> (I) wherein R1 is a prostaglandin or prostacyclin residue; Y is oxygen, sulfur, imino, or N-(C1-C4-alkyl) imino; Q is (CR6R7)p wherein p is an integer of 0 to 3; R2 is hydrogen; alkyl of 1-6 carbon atoms optionally substituted by hydroxy or amino; C1-C4-alkoxycarbonyl; benzyloxycarbonyl; cyano; or di-C1-C4-alkylaminocarbonyl; R3, R4, R5, R6 and R7 each independently is hydrogen; alkyl of 1-6 carbon atoms optionally substituted by hydroxy or amino; or aryl; and R3 and R4 together form a trimethylene, tetramethylene, or 1,3-butadienylene group when R2 and R5 together represent a direct bond; have valuable pharmacological properties, e.g., as blood-pressure-lowering or abortive agents. |
