发明名称 Improved process for the preparation of dihydro-1H-pyrrolizine-3,5-(2H,6H)-dione.
摘要 <p>Dihydro-1&lt;Underline style="single"&gt;H&lt;/Underline&gt;-pyrrolizine-3,5-(2&lt;Underline style="single"&gt;H&lt;/Underline&gt;,6&lt;Underline style="single"&gt;H&lt;/Underline&gt;)-dione is produced in higher overall yield in a process which comprises catalytically hydrogenating a lower alkyl ester of 4-(hydroxyimino)heptanedioic acid in the presence of a tri-(lower alkyl)amine, followed by cyclization of the product thus produced in the presence of a cyclizing agent such as acetic anhydride. </p>
申请公布号 EP0238088(A2) 申请公布日期 1987.09.23
申请号 EP19870104088 申请日期 1987.03.20
申请人 WARNER-LAMBERT COMPANY 发明人 HOEKSTRA, MARVIN SIMON
分类号 C07D207/26;C07D487/04;(IPC1-7):C07D487/04 主分类号 C07D207/26
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