发明名称 L-N-n-propylpipecolic acid-2,6-xylidide
摘要 The local anesthetic, L-N-n-propylpipecolic acid-2,6-xylidide, namely: <IMAGE> This compound is prepared by chlorinating L-pipecolic acid to yield the acid chloride, namely L-pipecolic acid chloride. The acid chloride is then reacted with 2,6-xylidine to yield L-pipecolic acid-2,6-xylidide. The L-N-pipecolic acid-2,6-xylidide is then propylated to yield the L-N-n-propylpipecolic acid-2,6-xylidide, which is a potent local anesthetic for humans and is of relatively low toxicity.
申请公布号 US4695576(A) 申请公布日期 1987.09.22
申请号 US19850785819 申请日期 1985.10.09
申请人 ASTRA LAKEMEDEL AKTIEBOLAG 发明人 AF EKENSTAM, BO T.;BOVIN, CHRISTER
分类号 C07D211/60;(IPC1-7):C07D211/60;A61K31/445 主分类号 C07D211/60
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