发明名称 NOVEL ORGANIC COMPOUNDS AND THEIR USE AS INTERMEDIATES IN THE PRODUCTION OF PHARMACEUTICALS
摘要 <p>There are disclosed compounds of the formula <CHEM> in which R<1> is an alkenyl or alkynyl group optionally substituted with an optionally substituted phenyl group and containing from 5 to 30 carbon atoms, and R<3>, R<4> and R<5> are each selected from hydrogen, carboxyl, C2-5 alkoxycarbonyl, C1-4 alkyl, C1-4 alkoxy, hydroxyl, optionally protected tetrazolyl, halo, trifluoromethyl, nitrile, nitro and -CONR2<1><0> where each R<1><0> is hydrogen or C1-4 alkyl. The compounds are intermediates useful for preparing pharmaceutical compounds of the formula <CHEM> in which R<1>, R<3>, R<4> and R<5> have the values given above and R<2> is optionally substituted phenyl or optionally substituted C1-10 alkyl.</p>
申请公布号 EP0201823(A3) 申请公布日期 1987.09.16
申请号 EP19860106093 申请日期 1984.07.31
申请人 LILLY INDUSTRIES LIMITED 发明人 BAKER, STEPHEN RICHARD;JAMIESON, WILLIAM BOFFEY;TODD, ALEC
分类号 A61K31/165;A61K31/10;A61K31/135;A61K31/16;A61K31/19;A61K31/195;A61K31/215;A61K31/22;A61K31/235;A61K31/275;A61K31/41;A61K38/00;A61P11/00;A61P37/08;A61P43/00;C07C17/26;C07C17/354;C07C33/20;C07C33/30;C07C67/00;C07C313/00;C07C315/02;C07C317/00;C07C317/14;C07C317/18;C07C317/28;C07C317/44;C07C317/46;C07C317/48;C07C319/14;C07C323/12;C07C323/16;C07C323/25;C07C323/52;C07C323/56;C07C323/58;C07C323/60;C07C323/65;C07D257/04;C07D257/06;C07D303/02;C07D303/04;C07D303/08;C07D303/12;C07D303/14;C07D303/32;C07D303/38;C07D303/40;C07D303/46;C07D307/88;C07D309/12;C07D405/10;C07K5/06;C07K5/062;(IPC1-7):C07D303/04 主分类号 A61K31/165
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