| 摘要 |
<p>Prodn. of diosmine (I) is effected by treating esperidine (II) with iodine in an inert organic solvent and eliminatinq HI with an organic base. - Pref. reaction is effected at between room temp. and 120 deg.C. The solvent is a polar aprotic solvent, esp. DMF, dimethylacetamide or DMSO. The base is pyridine or poly(4-vinylpyridine).</p> |
