| 发明名称 |
2-alkoxy-N-(1-azabicyclo¬2.2.2 -oct-3-yl) benzamide-N-oxides in the control of emesis caused by anticancer drugs |
| 摘要 |
Compounds for controlling emesis caused by anticancer drugs such as 2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamide-N-oxides have the formula:
<CHEM>
wherein R1 is a loweralkyl group and R2 represents hydrogen, halo, 4,5-benzo, methylsulphonyl loweralkoxy or amino group and n is 1 or 2, and the pharmaceutically acceptable acid addition salts thereof.
|
| 申请公布号 |
EP0237281(A1) |
申请公布日期 |
1987.09.16 |
| 申请号 |
EP19870301934 |
申请日期 |
1987.03.05 |
| 申请人 |
SYNTHELABO |
发明人 |
TENG, LINA CHEN;BEAREKMAN, STEPHEN CLYDE;TURNBULL, LENNOX BIRCKHEAD;ALPHIN, REEVIS STANCIL;SMITH, WILLIAM LEVI |
| 分类号 |
A61K31/435;A61P1/08;C07D453/02 |
主分类号 |
A61K31/435 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
