Long-life biomedical transcutaneous drug application device and method of transcutaneous application of drugs

摘要

To separate drugs within a chamber (66) formed beneath a dome-like housing (24) from another biomedically active substance, the chamber (66) is subdivided into two chamber portions (166, 266) by enclosing, within said chamber, a plastic bag (101) or by stretching a membrane (102) thereacross. The plastic bag, or the membrane, respectively, is ruptured upon depression of a terminal element (34) located at the apex of the dome of the housing. The subdivision of the chamber into two chamber portions prevents intermixing of the biologically active substances during storage. One of the chamber portions may retain liquids which are suitable in the article, and preferably are separated from another one of the liquids, such as a surfactant, and thus permits a wide choice, of, respectively, biologically active and other substances. Unintended leakage of the substances through a microporous membrane (76) closing off the housing is prevented by applying a cover strip across the membrane.