发明名称 2-amido 3(oxindol-3-yl)propionic acids having antiulcer activity
摘要 Novel oxindole derivative and salt thereof represented by the general formula, <IMAGE> wherein R1 is a hydrogen atom, a lower alkyl group, a lower alkenyl group, a lower alkynyl group or a phenyl-lower alkyl group; R2 is a hydrogen atom or a lower alkyl group; R3 is a hydrogen atom, a cycloalkylcarbonyl group, a benzoyl group which may have 1 to 3 substituents selected from the group consisting of a halogen atom, a lower alkyl group and a lower alkoxy group on the phenyl ring, or a phenyl-lower alkanoyl group which may have halogen atoms as the substituents on the phenyl ring; provided that when R4 is a hydrogen atom, then R3 should be neither a hydrogen atom nor a lower alkyl group. The novel oxindole derivative and salt thereof possesses anti-peptic ulcer effects and are useful as anti-peptic ulcer agents.
申请公布号 US4694017(A) 申请公布日期 1987.09.15
申请号 US19840610574 申请日期 1984.05.15
申请人 OTSUKA PHARMACEUTICAL CO., LTD. 发明人 UCHIDA, MINORU;KOMATSU, MAKOTO;NAKAGAWA, KAZUYUKI
分类号 C07D209/20;C07D209/34;(IPC1-7):A61K31/405 主分类号 C07D209/20
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