| 发明名称 |
PROCESS FOR PREPARING OPTICALLY-ACTIVE 3-ACYLTHIO-2-METHYLPROPIONIC ACID DERIVATIVES |
| 摘要 |
A process for resolving racemic 3-acylthio-2-methylpropionic acid esters by enantiospecific hydrolysis utilizing extracellular lipases of microbial origin (EC 3.1.1.3). The desired chiral products can be readily converted to captopril. |
| 申请公布号 |
WO8705328(A1) |
申请公布日期 |
1987.09.11 |
| 申请号 |
WO1987US00517 |
申请日期 |
1987.03.03 |
| 申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
SIH, CHARLES, J. |
| 分类号 |
C12P7/52;C12P7/62;C12P11/00;C12P19/18;C12P41/00;(IPC1-7):C12P11/00 |
主分类号 |
C12P7/52 |
| 代理机构 |
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代理人 |
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