| 发明名称 |
SUBSTITUTED 1-AZASPIRO(4.5)DECANES AND 1-AZASPIRO(5.5)-UNDECANES, INTERMEDIATES AND A PROCESS FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS |
| 摘要 |
The present invention relates to substituted 1-Azaspiro [4.5] decanes and 1-Azaspiro [5.5] undecanes of the general formula
<CHEM>
wherein R1 is hydrogen, -CO2R4, R4; R2 is hydrogen,
<CHEM>
R4 is alkyl of 1 to 4 carbon atoms, R5 is alkyl of 1 to 8 carbon atoms; X is halogen, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, CF3, and OH; m is an integer of 0, 1 or 2; and n is an integer of 1 or 2, and a process for their preparation. The compounds can be used as analgesics. |
| 申请公布号 |
DE3465080(D1) |
申请公布日期 |
1987.09.03 |
| 申请号 |
DE19843465080 |
申请日期 |
1984.02.03 |
| 申请人 |
HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED |
发明人 |
STRUPCZEWSKI, JOSEPH T.;GARDNER, BETH A. |
| 分类号 |
A61K31/40;A61K31/403;A61K31/435;A61P25/04;C07D209/54;C07D221/20;(IPC1-7):C07D209/54 |
主分类号 |
A61K31/40 |
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