发明名称 |
DERIVATIVES OF 4-(3-ALKYNYLOXY-2-HYDROXY-PROPYL)-PIPERAZIN-1-YL-N-PHENYL ACETAMIDE, THEIR PREPARATION AND THEIR THERAPEUTICAL USE |
摘要 |
1. Compounds of the formula : see diagramm : EP0143016,P9,F1 wherein R1 represents hydrogen or an alkyl radical linear or branched having 1-6 C atoms ; R2 and R3 represent separately a phenyl radical, an alkyl radical linear or branched having 1-6 C atoms, or together with the carbon atom to which they are bounded a cycloalkyl radical of 5 to 7 C atoms ; R4 represents hydrogen or an alkyl radical linear or branched having 1-6 C atoms ; R5 represents an alkyl radical linear or branched having 1-6 C atoms or phenyl radical optionally substituted by a halogen atom ; X represents hydrogen or halogen atom, and pharmaceutically acceptable addition salts thereof. |
申请公布号 |
DE3465085(D1) |
申请公布日期 |
1987.09.03 |
申请号 |
DE19843465085 |
申请日期 |
1984.09.14 |
申请人 |
RIOM LABORATOIRES- C.E.R.M. "R.L.-CERM" - (S.A.) |
发明人 |
COMBOURIEU, MICHEL;LAIGLE, JEAN-CLAUDE;REYJAL, JEAN-FRANCOIS;LANDES, MARIE-PAULE |
分类号 |
C07D295/14;A61K31/495;A61P9/08;A61P9/10;C07D295/15 |
主分类号 |
C07D295/14 |
代理机构 |
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代理人 |
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地址 |
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