| 摘要 |
NEW MATERIAL:A compound shown by formula I [D is H, halogen, OH, alkoxy, acyloxy, etc.; B is phenyl, thienyl or furyl; A is group shown by formula II, formula III (l is 0 or 1; m and n are >=1 and m+n is 2-8; R<1> is alkylamino, morpholino, piperidino, etc.,; R<2> is alkyl or OH) or group shown by formula IV (R<3> and R<4> are H, alkyl or acyl), etc.] and a salt thereof. EXAMPLE:3,4-Benzo-5-(2-dimethylamino)ethyloxyimino-1-phenyl-2-oxobicy clo[4,1,0]heptane. USE:Useful for improving and remedying symptoms based on organic disorder in the brain and pathergasia and also useful as a psychotropic agent. PREPARATION:For example, an oxabicycloheptanone derivative shown by formula V (D1 is H, halogen, alkoxy or benzyloxy) is reacted with hydroxyamine in the presence of a base, a prepared compound shown by formula VI and a prepared compound shown by formula VII are reacted with a compound shown by formula VIII (Y is halogen, etc.,) to give a corresponding compound shown by formula I. |
