发明名称 Lipid composition.
摘要 <p>A method of treating a relatively aged animal to reverse age-related changes in the lipid composition of organ and tissue cells, such as heart muscle cells, and the ability of the animal to withstand respiratory stress. A suspension of small unilamellar vesicles composed predominantly of egg phosphatidyl choline is administered parenterally to the animal, preferably over a period of several days and at a dose level of between about 0.1 and 1 grams lipid per kg body weight per day. Changes in the heart muscle cells are reflected in decreased levels of serum creatine phosphokinase. Lipo­some administration is continued until the serum crea­tine phosphokinase level drops at least about 50%. Also disclosed are liposome treatment methods for increasing longevity and male fertility. </p>
申请公布号 EP0234919(A2) 申请公布日期 1987.09.02
申请号 EP19870301595 申请日期 1987.02.24
申请人 HADASSAH MEDICAL ORGANIZATION 发明人 BARENHOLZ, YECHEZKEL;YECHIEL, ELISHALOM
分类号 A61K38/00;A61K9/127;A61K9/133;A61K31/685;A61P9/00;A61P15/00;A61P43/00 主分类号 A61K38/00
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