发明名称 |
Lipid composition. |
摘要 |
<p>A method of treating a relatively aged animal to reverse age-related changes in the lipid composition of organ and tissue cells, such as heart muscle cells, and the ability of the animal to withstand respiratory stress. A suspension of small unilamellar vesicles composed predominantly of egg phosphatidyl choline is administered parenterally to the animal, preferably over a period of several days and at a dose level of between about 0.1 and 1 grams lipid per kg body weight per day. Changes in the heart muscle cells are reflected in decreased levels of serum creatine phosphokinase. Liposome administration is continued until the serum creatine phosphokinase level drops at least about 50%. Also disclosed are liposome treatment methods for increasing longevity and male fertility. </p> |
申请公布号 |
EP0234919(A2) |
申请公布日期 |
1987.09.02 |
申请号 |
EP19870301595 |
申请日期 |
1987.02.24 |
申请人 |
HADASSAH MEDICAL ORGANIZATION |
发明人 |
BARENHOLZ, YECHEZKEL;YECHIEL, ELISHALOM |
分类号 |
A61K38/00;A61K9/127;A61K9/133;A61K31/685;A61P9/00;A61P15/00;A61P43/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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