COAGULATION-NEUTRAL, HYDROPHILIC GLASS FIBRES

摘要

Hydrophilic glass fibers which have bonded to their surfaces a layer of silane molecules of the formula are useful for the separation of plasma from blood for haemostasiological testing. In the formula: the molecule is bonded at its end oxygen to a surface of a glass fibre; R1 is C2-C6 alkylene; X is OH, C1-C6 alkoxy, having n carbon atoms and up to (n-1) OH groups in which n is 1-6, or an amino acid or peptide residue; and each of R'3 and R''3 is C1-C6 alkyl, an oxygen bridge to the silicon atom of another silane molecule or an oxygen bridge to the glass surface. The fibres have an average diameter of from 0.2 to 5 microns and a density of 0.1 to 0.5 g/cm3.