| 摘要 |
<p>The derivatives have the formula I <IMAGE> in which the hexose moiety is derived from D-glucose, D-mannose or D-galactose, n is 0 or 1, and R<1>, R<4> and R<6> are, independently of one another, lower alkanoyl or benzoyl, R<2> is lower alkyl or phenyl, R<3>, R<5> and R<7> are, independently of one another, hydrogen or lower alkyl, or R<5> and R<8> together are trimethylene and R<7> is hydrogen, R<8> is hydrogen or unsubstituted or phenyl-, hydroxyl-, mercapto- or lower alkylthio-substituted lower alkyl, R<9> and R<12> are, independently of one another, hydroxyl, amino, C1-10-alkoxy, aryl-lower alkoxy, alkanoyloxy-lower alkoxy with up to 16 C atoms, aroyloxy-lower alkoxy, 3-cholesteryloxy or 2-trimethylammonioethyloxy, R<10> is hydrogen, carboxyl, lower alkoxycarbonyl or aryl-lower alkoxycarbonyl and R<11> is hydrogen or unsubstituted or amino-, hydroxyl-, lower alkanoylamino-, lower alkanoyloxy-, 2-benzyloxycarbonylaminoethylsulphinyl-, 2-benzyloxycarbonylaminoethylsulphonyl-, 2-lower-alkoxycarbonyl- aminoethylsulphinyl-, 2-lower-alkoxycarbonylaminoethylsulphonyl- or guanidino-substituted lower alkyl, with the proviso that at least one of the radicals R<9> and R<12> is different from hydroxyl, amino and C1-7-alkoxy or R<10> is different from hydrogen, carboxyl and alkoxycarbonyl with up to 7 C atoms in the alkoxy moiety, and these compounds and salts thereof where appropriate can be used for the prophylaxis and therapy of viral infections.</p> |
