发明名称 UN PROCEDIMIENTO PARA LA PREPARACION DE ESTERES DEL ACIDO 1,4, DIHIDRO-3,5-PIRIDINCARBOXILICO.
摘要 <p>Compounds are described of the formula <IMAGE> (I) wherein R1 and R4 independently represent a C1-4 alkyl group; R2 and R3 independently represent a C1-6 straight or branched alkyl chain which may be interrupted by an oxygen atom; R5 represents a straight or branched chain C1-13 alkyl group or a C5-8 cycloalkyl group which may be substituted by a C1-3 alkyl substitutent; The compounds represented by formula (I) reduce intracellular calcium ion cencentration by limiting transmembranal calcium ion influx and thus may be useful for the treatment of cardiovascular disorders such as hypertension.</p>
申请公布号 ES552048(D0) 申请公布日期 1987.09.01
申请号 ES19480005520 申请日期 1986.02.14
申请人 GLAXO S.P.A. 发明人
分类号 A61K31/455;A61K31/435;A61P3/00;A61P9/00;A61P9/08;A61P9/10;A61P9/12;C07B;C07C;C07C69/76;C07D;C07D211/90;(IPC1-7):C07D211/86;A61K31/44 主分类号 A61K31/455
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