发明名称 |
Sialic acid derivative and process for preparing the same |
摘要 |
A novel N-acetylneuraminic acid derivative, represented by the general formula: <IMAGE> wherein the R1 groups are, independently, hydrogen or acetyl; R2 is a nucleoside residue; and R3 is carboxyl or methoxycarbonyl. The N-acetylneuraminic acid derivative is useful in inhibiting metastasis of cancer cells. Also provided is a process for the preparation of the derivatives.
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申请公布号 |
US4691012(A) |
申请公布日期 |
1987.09.01 |
申请号 |
US19850708638 |
申请日期 |
1985.03.06 |
申请人 |
KANTO ISHI PHARMA CO LTD |
发明人 |
OGURA, HARUO;FURUHATA, KIMIO;OSAWA, TOSHIAKI;TOYOSHIMA, SATOSHI;SHITORI, YOSHIYASU;ITO, MASAYOSHI;YOSHIMURA, SHOJI |
分类号 |
A61K31/70;A61K31/7042;A61K31/7052;A61K31/7064;A61K31/7072;A61K31/7076;A61P35/00;C07H19/04;C07H19/06;C07H19/067;C07H19/16;C07H19/167;(IPC1-7):C07H17/00 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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