发明名称 |
SPOSOB POLUCHENIJA 3,7-DIZAMEHHENNYKH PROIZVODNYKH 3-CEFEM-4-KARBONOVYKH KISLOT |
摘要 |
<p>Novel cephalosporin derivatives of the formula <IMAGE> wherein R<1> is hydrogen or a conventional amino-protecting group, and R<2> is a straight or branched alkyl group containing from 1 to 4 carbon atoms, allyl, 2- butenyl or 3-butenyl, or is a group <IMAGE> wherein R<3> and R<4> each are independently hydrogen, methyl or ethyl, or R<3> and R<4>, taken together with the carbon atom to which they are attached, may be a cycloalkylidene ring containing from 3 to 5 carbon atoms, and nontoxic pharmaceutically acceptable salts, physiologically hydrolyzable esters and solvates thereof exhibit potent antibacterial activity and can be incorporated into pharmaceutical compositions.</p> |
申请公布号 |
HU193158(B) |
申请公布日期 |
1987.08.28 |
申请号 |
HU19830000729 |
申请日期 |
1983.03.03 |
申请人 |
BRISTOL-MYERS CO,US |
发明人 |
ABURAKI,SHIMPEI,JP;KAMACHI,HAJIME,JP;NARITE,YUKIO,JP;OKOMURA,JUN,JP;NAITO,TAKAYUKI,JP |
分类号 |
C07D501/46;A61K;A61K31/545;A61K31/546;C07D;C07D417/04;C07D501/00;C07D501/04;C07D501/36;C07D501/38;C07D501/44;C07D501/56;(IPC1-7):C07D501/56 |
主分类号 |
C07D501/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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