LIPID A MONOSACCHARIDE ANALOG HAVING SUBSTITUTED HYDROPHILIC AND HYDROPHOBIC GROUP

摘要

NEW MATERIAL:The compound of formula I [X is group of formula II (n is integer of 5-15)]. EXAMPLE:6-O-[{2-deoxy-4-O-phosphoryl-3-O-tetradecanoyl-2-[(3RS)-3-tetr adecano yloxy-tetradecanoylamino]-D-glucopyranos-6-oyl}-6-(succinoylamino)-hex anoyl]- 1-deoxy-muramic acid dipeptide. USE:An antitumor agent. PREPARATION:The compound of formula I can be produced e.g. by converting the 6-site -O of 1-deoxy-muramic acid dipeptide to 6-atidohexanoyl, reacting with a D-glucopyranose compound of formula I having protected functional group and removing the protecting group from the reaction product.