发明名称 New 13-epi or D-homo steroids substituted in position 10 beta with a radical containing a double or triple bond, process for their preparation, their application as medicaments and the pharmaceutical compositions which contain them
摘要 Products of formula I: <IMAGE> in which R represents especially: H or optionally substituted alkyl, alkenyl, alkynyl, aryl and aralkyl radicals or alkoxy, carboxyl, dialkylamino and trialkylsilyl radicals, R6 and R7 represent especially either, together, a cyclopropyl or R6 = H and R7 = R1, R1 = H, alkyl, alkenyl, alkynyl or acetylthio, R2 = CH3 or ethyl, X and Y represent especially - either X = OH and Y = CH2CH2CO2M or CH2CH2CH2OH, - or X and Y together represent <IMAGE> - or X = OH and Y = H or R4, R4 = alkyl, alkenyl or alkynyl, n = 1 when R2 is in position alpha and n = 2 when R2 is in position beta , process for their preparation, their application as medicaments and the pharmaceutical compositions which contain them.
申请公布号 FR2594830(A1) 申请公布日期 1987.08.28
申请号 FR19860002511 申请日期 1986.02.24
申请人 ROUSSEL UCLAF 发明人 FRANCOIS NIQUE, ANDRE CLAUSSNER ET ANNE-MARIE MOURA;CLAUSSNER ANDRE;MOURA ANNE-MARIE
分类号 C07J15/00;C07J21/00;C07J63/00;C07J71/00;(IPC1-7):C07J19/00;A61K31/565;A61K31/585;C07J1/00 主分类号 C07J15/00
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