发明名称 ABIETAMIDE DERIVATIVE
摘要 NEW MATERIAL:An abietamide derivative expressed by formula I (R<1> is H, alkyl or substituted or unsubstituted phenyl; R<2> is H or alkyl; the dotted and solid lines are single or double bond). EXAMPLE:1-Phenyl-5-(DELTA<8>-dihydroabietoylamino)pyrazole. USE:A preventing and treating agent for arteriosclerosis capable of exhibiting improved cholesterol lowering action. PREPARATION:A DELTA<8>-dihydroabietic acid expressed by formula II or dehydroabietic acid expressed by formula III is condensed with the corresponding various amines to afford the aimed compound expressed by formula I.
申请公布号 JPS62190169(A) 申请公布日期 1987.08.20
申请号 JP19860031585 申请日期 1986.02.15
申请人 NIPPON SHINYAKU CO LTD 发明人 YOSHIKUNI YOSHIAKI;JOKAI SHOICHI;FUJITA MASAO;OZAKI TAKAYUKI
分类号 C07D231/40;A61K;A61K31/415;A61P3/06;A61P9/10;C07D275/02 主分类号 C07D231/40
代理机构 代理人
主权项
地址