发明名称 |
STABLE PROTEINS, METHODS FOR THEIR CONSTRUCTION, PLASMIDS AND OTHER DNA ENCODING THEM, CELL CULTURES HARBORING SUCH PLASMIDS |
摘要 |
Proteins are mutated in order to introduce disulfide linkages at sites not normally found in the wild type protein. Additional disulfide bonds formed in this fashion stabilize the proteins from inactivation. |
申请公布号 |
EP0155832(A3) |
申请公布日期 |
1987.08.19 |
申请号 |
EP19850301829 |
申请日期 |
1985.03.15 |
申请人 |
GENENTECH, INC. |
发明人 |
WETZEL, RONALD BURNELL |
分类号 |
C12N9/36;C12N15/10;C12P21/02 |
主分类号 |
C12N9/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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