摘要 |
A subcutaneous culture chamber for providing a priviledged site for studying infectious disease processes of microorganisms in laboratory animals consists of a pliable polyethylene cylinder with holes at each end. The cylinder can be collapsed and inserted in a flat injector of the plunger type which is employed to force the flattened cylinder through an incision in the skin of an animal into a subcutaneous site. After insertion, the chamber soon expands to operational size and the incision is closed. Thereafter the chamber is suitable for use as an infection site to study the pathogenesis and immunology of microorganisms or for obtaining, with a syringe and needle, tissue fluid usable in a serum bacteriological assay or other study.
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