摘要 |
Compounds of structure (I) …<CHEM>… in which Ar is furyl, thienyl, phenyl or phenyl which is substituted with 1 or 2 methoxy, hydroxy, halo or methyl groups; R is hydrogen, C3-6 allyl or C1-4-alkyl; and R<1> and R<2> are, each, hydrogen, C1-4alkoxy, hydroxy, halo or trifluoromethyl, at least one of R<1> and R<2> being other than hydrogen, and pharmaceutically acceptable acid addition salts thereof, processes for their preparation, pharmaceutical compositions containing them and their use in therapy as dopamine antagonists. |