LATEX AGGLUTINATION USING AVIDIN/BIOTIN SYSTEM

摘要

A reagent for detecting an analyte of interest in a sample fluid comprises: a) an inert particle; b) a plurality of avidin molecules noncovalently attached to the surface of the particle; and c) derivatized biotin molecules complexed with at least a portion of the avidin molecules, each such derivatized biotin molecule having the structure Formula (I), wherein A is a ligand specific for the analyte of interest and -R- is a linker group which covalently joins A to biotin.