Förfarande för franställning av som läkemedel användbara alkyl-(eller alkoxi-)-karbonyloxialkyl-7-/2-(2- aminotiazol-4-yl)-2-hydroxiiminoace tamido/-3-metoximetyl-3-cefem-4- karboxylat.

摘要

Compounds of formula (I): wherein: R<1> represents a methyl group; and R<2> represents a C1-C4 alkoxy group; and pharmaceutically acceptable acid addition salts thereof are valuable antibiotics suitable for oral administration. They may be prepared by reacting a compound of formula (II): (wherein X represents a halogen atom and R<1> and R<2> are as defined above) with thiourea.