摘要 |
The carboximide derivatives of the formula: <IMAGE> and pharmaceutically acceptable salts thereof; wherein X represents a group of the formula: <IMAGE> <IMAGE> <IMAGE> <IMAGE> <IMAGE> <IMAGE> <IMAGE> <IMAGE> <IMAGE> <IMAGE> <IMAGE> +TR <IMAGE> Z represents a hydrogen atom or a group of the formula: <IMAGE> wherein R represents an alkyl group, an aralkyl group, an aryl group, a cycloalkyl group, an alkenyl group, an arylalkenyl group, a pyridyl group or a substituted amino group; Y represents an alkyl group, an aralkyl group, an aryl group, a substituted or unsubstituted pyridyl group, a substituted or unsubstituted pyrimidyl group or a benzothiazolyl group; and m represents an integer of 2 or 3 and processes for the production thereof. The derivatives and their salts possess hypoglycemic activity and are useful for treating diabetes. |