| 摘要 |
NEW MATERIAL:The benzimidazolin-2-one derivative of formula I [R<1> is H, halogen, lower alkyl or lower alkoxy; R<2> is lower alkyl or aralkyl; Y is (branched) 2-4C alkylene chain; Z is secondary amino] and its acid addition salt. EXAMPLE:1-Benzyloxy-3-(2-diisopropylaminoethyl)benzimidazolin-2-one. USE:A remedy for ulcer having mild central activity and effective in remedying gastric ulcer, duodenal ulcer, etc., caused by stress, etc. PREPARATION:The compound of formula I can be produced by reacting a compound of formula II (most of which are known compounds) with an amine derivative of formula X-Y-Z (X is halogen or acid residue) or its acid addition salt in an inert solvent in the presence of a base.
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