Sebosuppressive benzoic acid ester derivatives and cosmetic preparations containing them

摘要

A cosmetic preparation for the treatment of seborrhea containing an antiseborrheically effective amount of a p-alkoxy or p-alkylbenzyloxy benzoic acid ester having the formula <IMAGE> wherein R1 is (i) a branched alkyl group having from 6 to 18 carbon atoms, (ii) an alkylbenzyl group wherein the alkyl moiety has from 3 to 9 carbon atoms, or (iii) R2-(O-Y)n wherein R2 is an alkyl group havig from 6 to 18 carbon atoms, or an alkylbenzyl group wherein the alkyl moiety has from 3 to 9 carbon atoms; Y is CHR3-CHR4; R3 and R4 independently represent a hydrogen or a methyl, and n=1 or 2; and R5 is an alkyl group having from 1 to 4 carbon atoms, or a methoxy alkyl, an ethoxyalkyl, or a hydroxyalkyl having from 1 to 4 carbon atoms; and further containing conventional vehicles and additives; the process for reducing mammalian sebum production by using the above cosmetic preparation and the p-alkoxy and p-alkylbenzyloxy benzoic acid esters themselves.