摘要 |
PURPOSE:To enable mass culture of an animal cell in high density, by using granules containing animal cells dispersed in collagen gel and culturing the animal cell by suspending the granules in a culture liquid. CONSTITUTION:Animal cells are dispersed in a collagen solution and the dispersion is gelatinized and cut to granular form. As an alternative method, animal cells are dispersed in a collagen solution and the dispersion is dripped to effect the gelation of the dispersion. Granules containing animal cells dispersed in collagen gel can be produced by this process. The animal cells are cultured by suspending the granules in a culture liquid.
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