| 摘要 |
<p>Novel compositions of matter and processes for their preparation. Particularly, the present invention relates to novel monocyclic β-lactams of formula (I), having a carbonyl group, other than a negatively charged group, attached to the N-1 position. These compounds are useful as antimicrobial agents or as intermediates thereto. The present invention also provides a novel process for making these compounds which utilizes palladium (O)-catalyzed carbonylation of an appropriate 2-bromo-1-propen-3-yl amine and novel intermediates prepared by this process.</p> |
