发明名称 |
HUMAN FACTOR VIII C |
摘要 |
Compositions having Factor VIII:C activity and immunologically cross-reactive with Factor VIII:C are prepared by the expression of genes encoding for the N-terminus and C-terminus of the Factor VIII:C gene, whereby each of those sequences has an independent signal sequence. The structural genes for the N- and C-termini may be on the same or different DNA constructs, each having independent transcriptional and translational regulatory signals. The construct(s) is/are introduced into mammalian cells whereby an active protein complex is produced having Factor VIII:C activity. |
申请公布号 |
AU6801487(A) |
申请公布日期 |
1987.07.30 |
申请号 |
AU19870068014 |
申请日期 |
1987.01.27 |
申请人 |
CHIRON CORP., NORDISK GENTOFTE |
发明人 |
RAE LYN BURKE;MIRELLA EZBAN RASMUSSEN |
分类号 |
C07K14/745;A61K38/00;A61K38/43;C07H21/04;C07K1/20;C07K1/22;C07K14/00;C07K14/755;C07K19/00;C12N5/00;C12N5/10;C12N15/00;C12N15/09;C12N15/85;C12P21/00;C12P21/02;C12R1/91 |
主分类号 |
C07K14/745 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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