发明名称 TERPENE DERIVATIVE
摘要 NEW MATERIAL:A terpene derivative expressed by formula I (R<1>, R<2> and R<3> are H or organic residue) or a nontoxic salt thereof. EXAMPLE:2, 4-Dimethyl-3-3-( 4-hydroxy-3-hydroxymethyl-1-butenyl )-4-(beta-D-glucop- yranosyl) oxymethyl-2-cyclohexen-1-one. USE:A treating and preventive agent for peptic ulcer. PREPARATION:For example, ethyl ether is added to a hot-water extract of cinnamon bark to carry out distribution and fractionation and a water-soluble fraction is recovered. The hot-water extract fraction is fractionated by suitably using normal phase adsorption chromatography, reversed phase chromatography and another chromatography in combination to give a compound expressed by formula II, which is then treated with glucosidase to afford the aimed com pound expressed by formula III.
申请公布号 JPS62174035(A) 申请公布日期 1987.07.30
申请号 JP19860248203 申请日期 1986.10.17
申请人 GREEN CROSS CORP:THE 发明人 SHIRAGAMI HIROSHIGE;FUKAYA TSUTOMU;SHIYOU TOSHIAKI;IWAI MASAKAZU;YOKOYAMA KAZUMASA;TABATA MAMORU;FUKUI HIROYUKI;TANAKA SHIGEO
分类号 C07C59/125;A61K31/12;A61K31/19;A61K31/215;A61K31/22;A61K31/33;A61P1/04;C07C45/00;C07C49/743;C07C49/753;C07C51/00;C07C67/00;C07C69/025;C07D325/00 主分类号 C07C59/125
代理机构 代理人
主权项
地址