6H-Isoxazolo[3,4-d]pyrazolo[3,4-b]pyridines, a process for their preparation and their use as medicaments.

摘要

There are disclosed compounds having the formula
<Chemistry id="chema01" num="0001"><Image id="ia01" he="46" wi="72" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry> wherein R₁ is hydrogen, loweralkyl, arylloweralkyl, aryl or heteroaryl; R₂ is hydrogen or loweralkyl; R₃ is loweralkyl, loweralkoxyloweralkyl, cycloalkyl, arylloweralkyl or heteroarylmethyl; and R₄ is hydrogen or loweralkyl; or a pharmaceutically acceptable acid addition salt thereof, which are useful as anxiolytic agents, methods for synthesizing them, and pharmaceutical compositions comprising an effective amount of such a compound.