发明名称 ANTI-CANCER DRUGS COMPRISING PLATINUM COMPLEXES
摘要 <p>There are provided anti-tumor agents comprising as active ingredient platinum complexed directly or via dextranamine moieties to an anti-tumor immunoglobulin. These are prepared by reacting an anti-tumor immunoglobulin or such immunoglobulin coupled to a dextran-amine with a platinum salt. Immunoglobulins having a specific binding activity towards certain types of cancer cells can be used. Immunoglobulins specific for ovarian or testicular carcinoma or for renal adenocarcinoma complexed directly or via dextran-amine moieties with platinum are effective agents for the treatment of these malignancies.</p>
申请公布号 CA1224718(A) 申请公布日期 1987.07.28
申请号 CA19830432233 申请日期 1983.07.12
申请人 YEDA RESEARCH AND DEVELOPMENT COMPANY LTD. 发明人 ARNON, RUTH;HURWITZ, ESTHER;KASHI, RINA;WILCHEK, MEIR;SELA, MICHAEL;SCHECHTER, BILHA
分类号 A61K39/395;A61K47/48;(IPC1-7):A61K39/395 主分类号 A61K39/395
代理机构 代理人
主权项
地址